Photoacoustic imaging of lacZ gene expression in vivo
نویسندگان
چکیده
منابع مشابه
Photoacoustic imaging of lacZ gene expression in vivo.
In the postgenomic era, imaging techniques are playing an important role in visualizing gene expression in vivo. This work represents the first demonstration of photoacoustic tomography (PAT) for reporter gene imaging. Rats inoculated with 9L/lacZ gliosarcoma tumor cells are imaged with PAT before and after injection of X-gal, a colorimetric assay for the lacZ-encoded enzyme beta-galactosidase....
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Photoacoustic molecular imaging, combined with the reporter-gene technique, can provide a valuable tool for cancer research. The expression of the lacZ reporter gene can be imaged using photoacoustic imaging following the injection of X-gal, a colorimetric assay for the lacZ-encoded enzyme β-galactosidase. Dual-wavelength photoacoustic microscopy was used to non-invasively image the detailed mo...
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ژورنال
عنوان ژورنال: Journal of Biomedical Optics
سال: 2007
ISSN: 1083-3668
DOI: 10.1117/1.2717531